Publications

  • Ruengsatra T, Soponpong J, Nalinratana N, Jirapongwattana N, Dunkoksung W, Rattanangkool E, Deesiri S, Srisa J,Songthammanuphap S, Udomnilobol U, Prueksaritanont T. Design, synthesis, and optimization of novel PD-L1 inhibitors and the identification of a highly potent and orally bioavailable PD-L1 inhibitor. Eur. J. Med. Chem; 2024 November 5, 277: 116730. DOI: https://doi.org/10.1016/j.ejmech.2024.116730.
  • Rattanangkool E, Srisa J, Deesiri S, Soponpong J, Wacharasindhu S, Vilaivan T, Prueksaritanont T. Development of In-Water Scalable Process for the Preparation of [2-(3-Bromo-2-methylphenyl)-7-chloro-1,3-benzoxazol-5-yl]methanol, a Key Intermediate in the Synthesis of Potent PD-1/PD-L1 Inhibitors. Synlett; 2024 July 01. DOI: 10.1055/s-0043-1774944.
  • Dunkoksung W, Udomnilobol U, Ruengsatra T, Chauypen N, Prueksaritanont T. Preclinical characterization of a novel potent core protein assembly modulator for the treatment of chronic hepatitis B viral infection. Eur. J. Pharm. Sci; 2024 September; 200:106834. DOI: https://doi.org/10.1016/j.ejps.2024.106834.
  • Udomnilobol U, Dunkoksung W, Sakares W, Jianmongkol S, Prueksaritanont T. Assessing the relative contribution of CYP3A-and P-gp-mediated pathways to the overall disposition and drug-drug interaction of dabigatran etexilate using a comprehensive mechanistic physiological-based pharmacokinetic model. Front. Pharmacol. Sec Translational Pharmacology; 2024 February;15:1356273. DOI: 10.3389/fphar.2024.1356273.
  • Soponpong J, Ruengsatra T, Nalinratana N, Udomnilobol U, Dunkoksung W, Rattanangkool E, Songthammanuphap S, Jirapongwattana N, Thavornsin N, Ampawa S, Srisa J, Deesiri S, Charoenpakdee C, Vilaivan T, Buranapraditkun S, Pisitkun T, Hirankarn N, Prueksaritanont T. 1,4-Diphenyl-1 H-indazole and 1-pyridin-2-yl-4-phenyl-1 H-indazole derivatives as PD-1/PD-L1 modulators for the treatment of cancer. International application No. PCT/US2023/068751 (Publication No. WO/2023/250335). The Patent Cooperation Treaty.
  • Nalinratana N, Jirapongwattana N, Udomnilobol U, Songthammanuphap S, Rattanangkool E, Thavornsin N, Deesiri S, Srisa J, Soponpong J, Ampawa S, Charoenpakdee C, Dunkoksung W, Ruengsatra T, Buranapraditkun S, Vilaivan T, Pisitkun T, Hirankarn N, Prueksaritanont T. 1371 Novel orally active and high tissue penetrant small molecules targeting surface and intracellular PD-L1 signals for cancer immunotherapy. J Immunother Cancer. 2023; 11. DOI: 10.1136/jitc-2023-SITC2023.1371.
  • Ruengsatra T, Meeprasert A, Rattanangkool E, Deesiri S, Srisa J, Udomnilobol U, Dunkoksung W, Chuaypen N, Kiatbumrung R, Tangkijvanich P, Vimolmangkang S, Pubhom K, Prueksaritanont T. Binding Characteristics of Pyrrole-scaffold Hepatitis B Virus Capsid Inhibitors and Identification of Novel Potent Compounds. RSC Adv. 2023; 13:29004-29022. DOI: 10.1039/d3ra04720b.
  • Udomnilobol U, Jianmongkol S, Prueksaritanont T. The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate. Drug Metab. Dispos. 2023 September; 51(9):1216-1226. DOI: 10.1124/dmd.123.001353.
  • Soponpong J, Ruengsatra T, Nalinratana N, Udomnilobol U, Ampawa S, Thavornsin N, Srisa J, Rattanangkool E, Charoenpakdee C, Chaiyakunvat P, Deesiri S, Songthammanuphap S, Dunkoksung W, Vilaivan T, Buranapraditkun S, Pisitkun T, Hirankarn N, Prueksaritanont T. 4-Phenyl-Indole Derivatives and Related Uses. International application No. PCT/US2021/065754 (Publication No. WO/2022/147302). The Patent Cooperation Treaty.
  • Ruengsatra T, Rattanangkool E, Chaiyakunvat P, Deesiri S, Dunkoksung W, Udomnilobol U, Chuaypen N, Tangkijvanich P, Pubhom K, Prueksaritanont T. Pyrolidine-3-Carboxide Derivatives and Related Uses. International application No. PCT/US2021/056267 (Publication No. WO/2022/087422). The Patent Cooperation Treaty.
  • Rattanacheeworn P, Kerr SJ, Kittanamongkolchai W, Townamchai N, Udomkarnjananun S, Praditpornsilpa K, Thanusuwannasak T, Udomnilobol U, Jianmongkol S, Ongpipattanakul B, Prueksaritanont T, Avihingsanon Y, Chariyavilaskul P. Quantification of CYP3A and Drug Transporters Activity in Healthy Young, Healthy Elderly and Chronic Kidney Disease Elderly Patients by a Microdose Cocktail Approach. Front. Pharmacol. 2021 September;12:726669. DOI: 10.3389/fphar.2021.726669.
  • Ngampanya A, Udomnilobol U, Sermsappasuk P, Pornputtapong N, Ongpipattanakul B, Patel N, Jianmongkol S, Prueksaritanont T. Development and Qualification of a Physiologically Based Pharmacokinetic Model of Finasteride and Minoxidil Following Scalp Application. J Pharm Sci. 2021 May;110(5):2301-2310. DOI: 10.1016/j.xphs.2021.02.016.